sif monothematic aging brain meeting
May 4th, 2017
14:00 - 15:15 Registration
15:15 – 15:25 Welcome address and meeting rationale
Gino Mirocle Crisci, Rector, Unical (Cosenza)
Sebastiano Andò, Head of Department of Pharmacy, Health Science and Nutrition, Unical (Cosenza)
Giacinto Bagetta, Chairman of Pharmacology, Unical (Cosenza)
15:25 – 15:30 Introduction
Laura Berliocchi (Catanzaro)
15:30 – 16:15 Opening lecture
“Age-related neurodegeneration”
Pierluigi Nicotera (Bonn)
16:15 – 16:30 Coffee break
16:30 – 16:55 Tribute to Norman George Bowery
Giacinto Bagetta (Cosenza) & Doug A. Richards (Birmingham)
In memoriam of Professor Norman G. Bowery
Stefano Tacconi (Verona)
SIF Medal to Barbara Joyce Bowery
Alessandro Mugelli (Florence), SIF (Elected) President
16:55 – 17:00 Introduction
Giuseppe Passarino (Cosenza)
17:00 – 17:30
“Genetics in dementia"
Amalia Bruni (Catanzaro)
17:30 – 19:30
FIRST ORAL COMMUNICATIONS
SESSION
Chairpersons: Maria Pia Abbracchio (Milan) & Luigi A. Morrone (Cosenza)
Critical Role Of Kv3.4 Potassium Channel And Nav1.6 Sodium Channel In Aβ Oligomer Effects On Neuron Excitability And Cognitive
Functions In Alzheimer’s Disease
Ciccone R, Franco C, Secondo A, Boscia F, Piccialli I, Anzilotti S, Vinciguerra A, Di Renzo GF, Annunziato L, Pannaccione A.
The modulation of intracellular Ca2+ homeostasis is involved in SOD1 and ApoSOD1-induced neuroprotection of motor neurons exposed to beta-methylamino-L-alanine
Petrozziello T, Tedeschi V, Pannaccione A, Boscia F, Di Renzo GF, Annunziato L, Secondo A.
Altered protein O-GlcNAcylation profile revealed by proteomics in AD: Novel insights on protein signalling mechanisms and potential therapeutic targets
Di Domenico F, Tramutola A, Sharma N, Barone E, Cassano T, Perluigi M.
Disturbance Of Ubiquitome Profile In Down Syndrome And Alzheimer’s Brain
Perluigi M, Tramutola A, Arena A, Barone E, Butterfield DA, Di Domenico F.
Effect Of Antidepressant Treatment On Neuronal Autophagic Flux
Cavaliere F, Adornetto A, Fornarelli A, Bertan F, Russo R, Bagetta G, Bano D and Nicotera P.
Anti-Inflammatory And Neuroprotective Effects Of Co-Ultrapealut In
A Mouse Model Of Vascular Dementia
Casili G, Siracusa R, Impellizzeri D, Cordaro M, Crupi R, Esposito E, Cuzzocrea S.
D-Aspartic Acid Ameliorates Cognitive Impairment In A Mouse Model Of Spared Nerve Injury And Reduces Β-Amyloid Aβ1-40 And Aβ1-42 Peptides
Iannotta M, Belardo C, D’Aniello A, Romano R, Luongo L, de Novellis V, Maione S.
Palmitoylethanolamide, Via PPAR-Alpha Receptor, Restores The Altered Synaptic Plasticity And Ameliorates The Compromised Pain-Related Behaviours In The Hippocampus In Neuropathic Mice.
Boccella S, Luongo L, Guida F, Belardo C, Iannotta M, Romano R, Marabese I, Palazzo E, de Novellis V, Maione S.
Influence Of Aging On Nociception In C57BL/6 Mice
Scuteri D, Berliocchi L, Morrone LA, Corasaniti MT, Sakurada T, Sakurada S, Bagetta G.
20:30 Social Dinner
May 5th, 2017
8:40 – 8:45 Introduction
Ferdinando Nicoletti (Rome)
8:45 – 9:15
“Aging and the Stressed Brain: From Mechanisms to Molecules"
Marco Riva (Milan)
9:15 – 10:45
SECOND ORAL COMMUNICATIONS SESSION
Chairpersons: Fabio Blandini (Pavia) & Diana Amantea (Cosenza)
Bioactivity Of Secondary Metabolites From Allium Species
Simin N, Četojević-Simin D, Mitić-Ćulafić D, Orčić D, Lesjak M, Nemeš I, Mimica-Dukić N.
N-Palmitoylethanolamide Prevents Parkinsonian Phenotypes In Aged Mice
Campolo M, Crupi R, Paterniti I, Filippone A, Lanza M, Cuzzocrea S, Esposito E.
CD4+ T Regulatory Cell In Peripheral Blood Of Parkinson’s Disease Patients
Kustrimovic N, Rasini E, Legnaro M, Aleksic I, Blandini F, Comi C, Marino F, Cosentino M.
Neuroprotective effects of temsirolimus in animal models of Parkinson's disease
Paterniti I, Casili G, Siracusa R, Cordaro M, Crupi R, Bruschetta G, Campolo M, Cuzzocrea S, Esposito E.
Modulation Of Autophagy To Achieve Retinal Neuroprotection
Varano GP, Adornetto A, Nazio F, Morrone LA, Corasaniti MT, Cecconi F, Nucci C, Bagetta G, Russo R.
Polymorphisms Of Dopamine Receptor Genes Are Associated To Risk Of Dementia In Patients With Parkinson's Disease
Ferrari M, Comi C, Marino F, Magistrelli L, Riboldazzi G, Bono G, Cosentino M.
Progressive Supranuclear Palsy-Like Phenotype Secondary To Brain Vascular Lesions
Mancini M, Garcea T, Morelli M, Mastroianni G, Arabia G, Lupo A, Manfredini LI, Nicoletti G, Salsone M, Novellino F, Bono F, Mazza M,
Ferrigno G, Rocca F, Chiriaco C, Cascini GL, Quattrone A.
10:45 – 10:55
Coffee Break
10:55 – 11:00 Introduction of the first Keynote lecture
Rossella Russo (Cosenza)
11:00 – 11:45 Keynote lecture
“Protein S-Nitrosylation, Synapse Loss, and NMDA Receptor Drug Development for Alzheimer’s Disease"
Stuart A Lipton (San Diego)
11:45 – 13:15
THIRD ORAL COMMUNICATIONS
SESSION
Chairpersons: Marco Cosentino (Varese) & Anna Pittaluga (Genoa)
Biliverdin Reductase-A Mediates The Beneficial Effects Of Intranasal Insulin Administration On Alzheimer Disease Pathology In The Brain Of 3xTg-AD Mice
Barone E, Triani F, Tramutola A, Cassano T, Butterfield DA and Perluigi M.
Dimethyl Fumarate, NRF2 Dependent, As A New Therapeutic Approach For Amyloid Beta Induced Oxidative Stress
Lanza M, Campolo M, Casili G, Filippone A, Paterniti I, Cuzzocrea S, Esposito E.
Vildagliptin Improves Animal Behavior And Cognitive Impairment In A Rat Model Of Streptozotocin Induced Diabetes
Russo E, Palleria C, De Sarro C, Leo A, De Caro C, Citraro R, De Sarro G.
Impact Of Legumes And Plant Proteins Consumption On Cognitive Performances In The Elderly
Ferro Y, Mazza E, Fava A, Moraca M, Rotundo S, Provenzano F, Greco M, Foti D, Gulletta E, Bosco D, Montalcini T, Pujia A.
Immunotherapies For Alzheimer's Disease: Clinical Trials Evaluation, State Of The Art And Future Prospects
De Fina M, De Francesco A, Naturale MD, De Sarro G.
Distinct Anxiolytic Profile of Bergamot Essential Oil in Preclinical Behavioural Studies
Tridico L, Rombolà L, Corasaniti MT, Sakurada T, Sakurada S, Bagetta G, Morrone LA.
Pharmacological Basis For The Treatment Of Behavioural and Psychological Symptoms Of Dementia (BPSDs) With Aromatherapy
Scuteri D, Morrone LA, Rombolà L, Russo R, Berliocchi L, Corasaniti MT, Sakurada T, Sakurada S, Bagetta G.
13:15 – 13:20 Presentation of Closing Keynote lecture
Pierluigi Nicotera (Bonn)
13:20 – 14:05
Keynote lecture
“Modulating Innate Immunity in Alzheimer’s disease "
Michael Heneka (Bonn)
14:05 General discussion
14:15 – 15:30 Light Lunch and Posters discussion
15:30 Round Table
“Aging Brain: New Vistas in Drug Discovery Process”
Fabio Blandini (Pavia)
Ferdinando Nicoletti (Rome)
Carlo Nucci (Rome)
Anna Pittaluga (Genoa)
Laura Berliocchi (Catanzaro)
Marco Cosentino (Varese)
POSTERS
Analysis Of The Use Of Drugs For The Treatment Of Alzheimer's Dementia In Calabria Region
Garreffa MR, De Francesco AE, Labate D, Mirarchi S, Florio L.
Environmental training on clinical symptoms and synaptic defects in aged mice: a pre-clinical study to support the rehabilitative approach in clinic
Bonfiglio T, Vergassola M, Olivero G, Scimone A, Pittaluga A.
Analysis Of Adverse Reactions To Drugs In Patients With Alzheimer's Disease Or Other Dementias: Calabria Region Analysis Of ADR
Fersini G, De Francesco AE, Maione MR, Naturale MD, Esposito S, Zito MC.
The Impact Of Natural Products On Arachidonic Acid Metabolism During Inflammation
Mimica-Dukić N and Simin N.
Prescribing Appropriateness And Analysis Of The Potential Interactions In The Population Of The Elderly Treated With
Anticholinesterase Drugs Within The Health District Of Cosenza (Asp)
Altimari I, Rosselli A, Piro B, Vulnera M.